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Company description
晶泰科技(XtalPi)是一家以人工智能和机器人技术为核心驱动力的创新型研发平台公司。依托量子物理、AI、云计算和机器人实验等前沿技术,晶泰科技基于高质量垂类数据训练行业专属AI模型,并通过机器人自动化技术实现精准的化学执行与数据治理,构建高效闭环迭代体系,加速新物质的发现与研发。
晶泰科技广泛服务于生物医药、材料科学、能源化工等多个行业,致力于为合作伙伴提供从分子设计到实验执行的全流程创新解决方案,推动行业研发范式的深刻变革。
智能自主实验平台
- XmartChem® 智能合成工作站:面向化学合成场景的自动化工作站,提升合成效率与数据质量。
- XtalComplete® 智能结晶工站:专为药物结晶研究设计的自动化实验设备。
- ChemPlus® 桌面型固体加样仪:适用于固体样品精准加样的桌面级自动化仪器。
- 智能电解液工作站:面向新能源电池领域,支持电解液配制和表征的自动化工作站,助力新能源电池研发效率提升。
AI 软件应用
- PatSight(XInsight)药物专利挖掘平台:帮助研发科学家高效提取和分析药物专利数据,快速洞察化学空间。
- XFEP 自由能微扰亲和力预测平台:高精度自由能计算工具,用于分子结合亲和力的精准预测。
- XMolGen 多功能分子设计软件:生成式化学工具,支持全新化学空间的深入探索与优质候选分子的快速锁定。
药物发现解决方案
- 小分子药物发现平台:依托AI与自动化技术,支持从靶点发现到临床前候选药物研发的全流程探索,为药物研发全流程提速增效。
- Ailux 抗体药物发现:面向抗体类药物的发现与优化服务。
- 生物学能力:提供涵盖苗头化合物发现、苗头/先导化合物优化及生物学评价的综合能力支持。
药物固体形态研发
- Xtalgazer® 新一代药物结晶研发平台:集晶型预测技术、结晶策略推荐技术和自动化实验技术于一体,全面提升固态研究的效率与质量。
- 药物结晶实验研究:提供系统化的实验固态研发服务。
- 固态化学计算服务:运用计算化学方法支持固体形态的深入研究,包括杂质排除策略的计算指导。
- 晶体结构解析与电镜服务(MicroED):提供包括MicroED在内的先进晶体结构鉴定技术,突破ASD体系中微量晶体快速鉴定的技术瓶颈。
未来化学与发现化学
- 一站式化学服务:整合自动化化学合成与聚焦化合物库构建,为药物发现提供全面的化学支持。
- 自动化化学合成:利用机器人自动化技术实现高通量、高质量的化学合成执行。
学术成果与技术积累
- 晶泰科技在药物固体形态、分子设计、结构生物学等领域持续发表高水平学术论文,研究成果涵盖多晶型结构差异分析(如Nirmatrelvir/Paxlovid固体形态研究)、聚合物基底上的模板成核机制、表位预测的多模态联合表征(WUREN)等前沿课题。
- 团队曾在28天内针对GPX4靶点发现新型非共价强效苗头化合物,并首次通过冷冻电镜技术展示SARM1的作用机制,体现了平台的快速迭代与技术突破能力。
晶泰科技通过软硬件一体化的全景产品布局,从AI软件平台到智能实验室硬件,从小分子药物发现到材料与能源化工领域的智慧实验室建设,全方位赋能行业研发创新,持续推动微观分子世界探索的边界向前延伸。
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